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Management of Simple Nodular Goiter in Adults: Current Status and Future Perspectives.
Egypt (IFMSA-Egypt) - Suez Canal University, Suez Canal
Department of Surgery & Department of Pathology, Faculty of Medicine,Suez canal Univer
Prof. Dr.Osama Antar (Surgery department)
dr.mohamed adel el sayed
Type of Research Project
- Clinical Project with Laboratory work
What is the background of the project?
The simple nodular goiter, the etiology of which is multifactorial, encompasses the spectrum from the incidental asymptomatic small solitary nodule to the large intrathoracic goiter, causing pressure symptoms as well as cosmetic complaints. Its management is still the cause of considerable controversy. The project aims at supporting diagnostic evaluation in relation to functional and morphological characterization with serum TSH and (some kind of) imaging as well as emphasizing on the importance of ruling out malignancy through use of fine-needle aspiration biopsy (cytology) as most patients need no treatment after malignancy is ruled out. In case of cosmetic or pressure symptoms, the choice in multinodular goiter stands between surgeries, which is still the first choice, and radioiodine if uptake is adequate. In addition to surgery, the solitary nodule, whether hot or cold, can be treated with percutaneous ethanol injection therapy. If hot, radioiodine is the therapy of choice. Randomized studies are scarce, and the side effects of nonsurgical therapy are coming into focus. Therefore, the use of the optimum option in the individual patient cannot at present be based on evidence. However, we are of the view that levothyroxine, although widely used, should no longer be recommended routinely for this condition. Also recombinant human TSH and laser therapy may profoundly alter the nonsurgical treatment of simple nodular goiter.
What is the aim of the project?
The study aims to evaluate treatment options for simple nodular goiter patients and their outcomes.
What techniques and methods are used?
Clinical and lab evaluation of patients previously diagnosed as they had SNG and was treated by surgery, radioactive iodine or thyroid suppressor drugs then comparing treatment options outcomes.
What is the role of the student?
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- If the project includes “lab work”
- the student will take active part in the practical aspect of the project
- If the project is clinical
- the student will take active part in the clinical examination
- If the project is clinical
- the student will be allowed to work with patients
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
Collecting medical history. Performing general and local examination. Collecting blood samples for lab measurements. Collecting the data about thyroid function tests and then contributing in giving results. Aiding in performing neck ultrasound. Study and explain the basics of thyroid diseases and their causes.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
Theoretical teaching about history, examination, clinical skills, interpreting lap results in form of lectures and clinical talks.
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a scientific report
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
The student should have finished at least the Endocrine curriculum regarding the thyroid (which should include basic anatomy, histopathology, physiology and biochemistry) in his/her home country.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months)
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