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Physiological analysis of sensory neuronal synaptic transmission and in vivo patch- clamp recordings
Japan (IFMSA-Japan) - Hyogo Medical University, Hyogo(Kansai area)
Dept Neurophysiology, Hyogo Medical College of Medicine 1-1 Mukogawa, Nishinomiya 663-8501, Japan
K. Koga, H. Furue
Type of Research Project
- Basic science
What is the background of the project?
Our lab will provide for students or young researchers an excellent opportunity to experience cutting-edge experimental methods, in particular, electrophysiological techniques to detect single-cell neuronal responses in the CNS by themselves. For example, the spinal cord has an important role in the transmission and modulation of sensory information. Spinal dorsal horn neurons make excitatory synaptic contacts with sensory primary afferent fibers. In addition, dorsal horn neurons receive inhibitory synaptic inputs from spinal interneurons and descending inhibitory neurons in the brain stem. You can study the spinal modulatory mechanism of sensory transmission by using electrophysiological tools such as in vivo patch-clamp recording techniques. Behavioral and immunohistochemical analyses for the neuronal mechanism of sensory transduction can be also used.
What is the aim of the project?
To provide for students or young researchers an excellent opportunity to experience cutting-edge electrophysiological experimental methods
What techniques and methods are used?
Patch-clamp recording, Extracellular recording, Behavioral and immnunohistochemical analysis
What is the role of the student?
- The student will observe the practical experiments but will be highly involved in the analysis of the results
What are the tasks expected to be accomplished by the student?
Experimental methods such as Patch-clamp recording, Extracellular recording, Behavioral and immnunohistochemical analysis
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
Lectures and data analysis
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a presentation
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
We expect no prior experience with experimental techniques. Understanding synaptic transmission and apoptotic pathway will help the student to better prepare for the student project..
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students
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