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Biobanking and translational research of new biomarkers and drug targets
Spain (IFMSA-SPAIN)-University of Santiago de Compostela, Santiago de Compostela
Pathology , Clinical Hosp and Research Group of the Health Research Institute(IDICHUS
Dr. Jose Ramon Antunez Lopez
Maximo Fraga Rodriguez, Orlando Fernandez Lago and Jose Ramon Antunez Lopez.
English, spanish, french
Type of Research Project
- Basic science
What is the background of the project?
This is particularly important in rare diseases or subgroups of common ones, for clinical trials, and for validating new biomarkers and drug targets. Biobanking requires collaborative work and interaction with a large network of professionals including researchers, clinicians, pathologists, laboratory staff and other biobanks. To ensure the quality of the material provided to the researcher, and also to respect the interests of both the scientific and the patient, well defined protocols must be followed. Hospital biobanks are usually linked to the pathology department, as is our case, so they offer the opportunity to see the interaction between daily diagnosis and research work.
What is the aim of the project?
The goal of biobanking is to accelerate the progress of translational medicine by providing the researcher with sufficient numbers of biospecimens and data of trustable quality. This is particularly important in rare diseases or subgroups of common ones, for clinical trials, and for validating new biomarkers and drug targets.
What techniques and methods are used?
Sample selection and preservation (especially freezing procedure). Tissue microarray construction. DNA extraction. Ancillary techniques commonly used in translational research: Immunohistochemistry, FISH, PCR. Processing amd storing tissues for transplantation. Freeze-drying (lyophilization) procedures.
What is the role of the student?
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
To get the students familiar with all the procedures involved in biobanking into a pathology department. To increase the knowledge about the essential role of biobanking in supporting high-quality research and network scientific cooperation. To improve the quality of the samples that biobanks provide to researchers. To help students become familiar with the procedures of a musculoskeletal bank for the collection, processing and distribution of tissue grafts To show students the latest developments in research related to biobanking tissues intended for therapeutic purposes. Techniques learnt: Sample selection and preservation (especially freezing procedure). Tissue microarray construction. DNA extraction. Ancillary techniques commonly used in translational research: Immunohistochemistry, FISH, PCR. Processing amd storing tissues for transplantation. Freeze-drying (lyophilization) procedures.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- No specific outcome is expected
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Minimal knowledge of lab routine (for example: solution preparation, calculate concentrations
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months) - Pre-Medical students from the American-British system
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