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The role of fetal DNA in pre-eclampsia
Institute of Molecular Biomedicine, Medical faculty, Comenius University in Bratislava
Peter Celec, MD, MSc., Ing, PhD., MPH
Julius Hodosy, MD, MSc., PhD., MPH
Type of Research Project
- Basic science
What is the background of the project?
Pre-eclampsia and resulting eclampsia are serious and potentially life threatening disorders of mother and/or her fetus. The pathogenesis and therefore casual treatment is still missing. Several recent works suggest, that fetal DNA in maternal plasma and subsequent immune response activation could play the role, but the evidence is thin.
What is the aim of the project?
. The aim of the project is to describe the possible role of fetal DNA in pathogenesis of preeclampsia.
What techniques and methods are used?
PCR, RT-PCR, electrophoresis, animal experiments, DNA and RNA isolation, sequencing.
What is the role of the student?
What are the tasks expected to be accomplished by the student?
Only a will to work at laboratory.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- No specific outcome is expected
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Only a will to work at laboratory. Basic knowledge of good laboratory practice is suitable. Will to work with experimental animals. There are no legal limitations in themstudent`s involvement in the project.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students
- www.imbm.sk in section "Students studying in English" and "Publications"
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