Molecular pharmacology of voltage-gated ion channels
Universita degli studi di Campobasso
Dept. of Medicine and Health Science, University of Molise
Prof. Guido Maria Grasso
Maria Virginia Soldovieri (
English, Italian, French
4 weeks
Cities/Months Jan Feb Mar Apr May Jun Jul Augt Sep Oct Nov Dec
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Type of Research Project
- Basic science
What is the background of the project?
Our research group is interested in studying the molecular pathophysiology and pharmacology of several groups of ion channels, with particular emphasis on voltage-gated potassium channels encoded by the KCNQ2 and KCNQ3 genes. These have been mainly involved in monogenic epilepsies of the neonate, but are also expressed in the peripheral nervous system, in sensory organs, and skeletal muscle.
What is the aim of the project?
Our aim is to identify compounds which specifically target ion channels which might be of help in treating diseases of the nervous system, of the cardiovascular system, and skeletal muscle.
What techniques and methods are used?
In the lab we currently use routine cellular (cell cultures, immunocytochemistry,
What is the role of the student?
- If the project includes “lab work”
- the student will take active part in the practical aspect of the project
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- No specific outcome is expected
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
A basic undergraduate knowledge in biology is required.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts:
- Medical students
- Graduated students (less than 6 months)
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