Projects
Name
Oligodendrocyte in animal model of multiple sclerosis
University
Asahikawa Medical University
Domain
Pathology
Departement
Department of Fuctional Anatomy Nd Neuroscience, Asahikawa Medical College
Head
Professor Shigetaka Yoshida, M.D. Ph.D.
Tutor
Yoshio Bando,Ph.D.
Languages
English/Japanese
Duration
4 weeks
Availability
Cities/Months Jan Feb Mar Apr May Jun Jul Augt Sep Oct Nov Dec
Yes Yes Yes Yes Yes Yes Yes Yes No No No No
Type of Research Project
- Basic science
What is the background of the project?
We study behavioral and histological change in experimental allergic encephalitis (EAE) ,pathological model of multiple sclerosis (MS) in lab animals. Immune reactions are thought to be most important in understanding pathology of MS and EAE. However,we found that proteases expressed in oligodendrocytes play important roles in demyelination and cell death of oligodendrocytes.
What is the aim of the project?
The aim of the project is to find out how these proteases are related to the pathology.
What techniques and methods are used?
We use mice and histological and biochemical techniques.
What is the role of the student?
- The student will observe the practical experiments but will be highly involved in the analysis of the results
What are the tasks expected to be accomplished by the student?
To understand behavioral and histological change in experimental allergic encephalitis (EAE) ,pathological model of multiple sclerosis (MS) in lab animals. It's necesarry to understand Immune reactions of animals. So we teach students a general way of observing a immune reaction with some specific method.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
There is no preliminary readings. However,there will be some lectures and seminars to be attended,only when they are held in English. There may be some Round-Table discussions in English. What is the role of the student and what is expected from him/her during the research exchange? What should be the outcome of the student
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a poster
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Undergraduate level of knowledge on the central nerbous system and molecular biology.
There is no legal limitations in the student
Are there any legal limitations in the student’s involvement
No
Hours
6
Type of students accepted
This project accepts:
- Medical students
Articles
- none