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In vitro study on the role of neutrophils in psoriasis pathogenesis
CMDGT/LOEX Hopital de l'Enfant-Jesus
Francois A. Auger M.D.
Roxane Pouliot Ph.D
English or French
Type of Research Project
- Basic science
What is the background of the project?
What is the aim of the project?
To understand the role of neutrophils in psoriasis, we elaborated an in vitro model using cultured psoriatic keratinocytes with T lymphocytes and neutrophils.
What techniques and methods are used?
Techniques used include cell culture, flow cytometry, ELISA, immunofluorescence and RT-PCR.
What is the role of the student?
- The student will observe the practical experiments but will be highly involved in the analysis of the results
- The tasks will be done under supervision
What are the tasks expected to be accomplished by the student?
Roles of the student will be to observe and participate to the analysis of a graduated student. It is an observation training, there will be no paper and no poster. Student will acquire theorical knowledge on the skin, psoriasis, tissue engineering and immunology. Technical abilities in cell biology will be developed (FACS, IHC and ELISA).
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
Preliminary readings and lectures will be provided.
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- No specific outcome is expected
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Student must have some technical abilities, appreciate teamwork, interests on skin, psoriasis and tissue engineering and basic knowledge in immunology. No specific level of studies is necessary.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students
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