Role of purinergic P2X7 receptors in the function of lymphocytes and macrophages
Germany (bvmd) - Martin-Luther-Universitaet Halle-Wittenberg, Halle a.d.Saale
Martin-Luther-University Halle, JB Inst for Physiology; Magdeburger Str. 6, D-06097 Halle
Prof. Dr. M. Gekle
Prof. Dr. F. Markwardt
Fluent English or German
4 weeks
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Type of Research Project
- Basic science
What is the background of the project?
Investigation of how ATP-receptors (P2X) influence the function of microglia cells through measurement of ionic currents, intracellular Ca2+-signals by Ca2+-fluorescent dyes, measurement of glia cell migration by voltage clamp and immune-fluorescence techniques. -Structure-function-relationship of P2X receptors by voltage clamp (whole cell and single ion channels) and fluorescence techniques (FRET). This project accepts: - Students of Biophysics, Medicine, Biology and Pharmacy
What is the aim of the project?
What techniques and methods are used?
What is the role of the student?
What are the tasks expected to be accomplished by the student?
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
The student can participate in the lecture of Physiology for medical students (only during lecture periods) and in a tutorial about the function of ion channels.
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Basic knowledge in cell physiology is required! Please do only apply if you fulfill this requirement. FLUENT English is absolutely necessary!
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts:
- Medical students
- Students in biomedical fields
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