Projects
Name
Molecular studies on neural development
University
University of Tsukuba
Domain
Neurology
Departement
Department of Molecular Neurobiology, Faculty of Medicine
Head
Masayuki Masu, M.D., Ph.D.
Tutor
Kazuko Keino-Masu, Kensuke Shiomi, Takuya Okada
Languages
English/Japanese
Duration
4 weeks
Availability
Cities/Months Jan Feb Mar Apr May Jun Jul Augt Sep Oct Nov Dec
Yes Yes Yes No No Yes Yes Yes Yes No Yes Yes
Type of Research Project
- Basic science
What is the background of the project?
The aim of the project is to study the molecular mechanism of how neural systems are formed. To this end, the genes and proteins involved in neural development are examined using molecular biological and histological techniques. The animals used are genetically manipulated or mutant mouse and zebrafish embryos.
The techniques and methods used are RT-PCR (reverse transcription-polymerase chain reaction), Northern blot, Western blot, in situ hybridization, immunohistochemistry.

Short lectures on the theoretical background concerning the experimental procedures will be provided if necessary.

The students should learn the principles of experimental procedures and perform all the experiments by themselves. The outcome is not mandatory.
The students will acquire basic skills on molecular biology and some
knowledge on vertebrate development.

Further information;
Cell vol. 87, pp. 175-185, 1996. Genes to Cells vol. 7, pp. 173-186, 2002. Current Biology vol. 13, pp. 73-77, 2003. Brain Research Molecular Brain Research vol. 135, pp. 169-180, 2005.
What is the aim of the project?
The aim of the project is to study the molecular mechanism of how neural systems are formed. To this end, the genes and proteins involved in neural development are examined using molecular biological and histological techniques. The animals used are genetically manipulated or mutant mouse and zebrafish embryos.
What techniques and methods are used?
The techniques and methods used are RT-PCR (reverse transcription-polymerase chain reaction), Northern blot, Western blot, in situ hybridization, immunohistochemistry.
What is the role of the student?
What are the tasks expected to be accomplished by the student?
RT-PCR (reverse transcription-polymerase chain reaction), Northern blot, Western blot, in situ hybridization, immunohistochemistry.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
Short lectures on the theoretical background concerning the experimental procedures will be provided if necessary.
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- No specific outcome is expected
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Basic knowledge on molecular biology, histology, and vertebrate development is reuquired.
Are there any legal limitations in the student’s involvement
Yes
The students need to participate in a lecture on animal experiment
Hours
7
Type of students accepted
This project accepts:
- Medical students
Articles
- a:0:{}