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Introduction of global hypomethylation by reactive oxygen species in bladder cancer cell lines
Thailand (IFMSA-Thailand) - Faculty of Medicine, Chulalongkorn University, Bangkok
Department of Biochemistry, Chulalongkorn University
Assist. Prof. Dr. Pisit Prapunwattana
Assist. Prof. Dr. Chanchai Boonla
Type of Research Project
- Basic science
What is the background of the project?
Bladder cancer is a common urologic cancer that has the highest recurrence rate of any malignancy. The most common type is transitional cell carcinoma. Other types of bladder cancer includes squamous cell carcinoma and adenocarcinoma. As other studies have shown that the risk of developing bladder carcinoma is 2-6 times greater in smokers (regular tobacco use) than in non-smokers. The project aims to study the molecular biology and genetic components of transitional epithelial cells in the patients with bladder cancer.
What is the aim of the project?
This project aims to study the molecular biology and genetics of transitional epithelial cells in the patients with CA bladder.
What techniques and methods are used?
Molecular biology and genetic studies technique
What is the role of the student?
- The student will mainly observe
- The student will observe the practical experiments but will be highly involved in the analysis of the results
What are the tasks expected to be accomplished by the student?
The students will allowed to use a high-technology labaratory instruments to study the molecular biology of these malignant cells in affected patients, learning the clinical signs and symptoms of the infected patients, review the research papers with the tutors and other students.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a scientific report
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Basic Science Knowledge. Required participation in the lab, at least 80% of the duration of the program.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students - Graduated students (less than 6 months) - Pre-Medical students from the American-British system - Students in biomedical fields
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