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Neuroendocrine-based stress study in physiology
Japan (IFMSA-Japan) - University of Occupational & Environmental Health Medical, Fukuoka
Department of Physiology, School of Medicine, University of Occupational and Environmental
Yoichi Ueta, M.D., Ph.D.
Takashi Maruyama, Lecturer; Mitsuhiro Yoshimura, Assistant Professor
Type of Research Project
- Basic science
What is the background of the project?
Recently, the job stress has been increased in work place. It is very important to understand the physiological mechanism of stress-induced reactions that are involved in autonomic, neuroendocrine and immune functions in the whole body.
What is the aim of the project?
The aim of the project is to understand and investigate what occurs in the brain during stress and how stress reaction in the whole body is caused, using animal models.
What techniques and methods are used?
Using genetically modified animal model neuronal activations in the hypothalamus and other brain areas during stressful conditions will be measured by neuroanatomical, molecular biological and electrophysiological approaches.
What is the role of the student?
- The student will mainly observe
- The student will observe the practical experiments but will be highly involved in the analysis of the results
What are the tasks expected to be accomplished by the student?
The tutors guide and teach the student what/how he/she perform experiments during stay in our lab. After he/she finish the project, he/she will present obtained data and discuss with our lab members.
Will there be any theoretical teaching provided (preliminary readings, lectures, courses, seminars etc)
Although we have no specific plan to teach theoritical teaching, we give several scientific papers related to the experiment and attendance of the research seminar in our lab.
What is expected from the student at the end of the research exchange? What will be the general outcome of the student?
- The student will prepare a presentation
What skills are required of the student? Is there any special knowledge or a certain level of studies needed?
Basic knowledge of neurophysiology and endocrinology. It is necessary to adapt animal (rats and mice) care and experiments.
Are there any legal limitations in the student’s involvement
Type of students accepted
This project accepts: - Medical students
- Hypothalamic vasopressin response to stress and various physiological stimuli: visualization in transgenic animal models. Ueta Y; Dayanithi G; Fujihara H.Horm Behav. 2011 Feb;59(2):221-6. doi: 10.1016/j.yhbeh.2010.12.007. Epub 2010 Dec 23. Review.
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