We are more than pleased to welcome you in the capital city of Chile, Santiago de Chile!!! This city would be your option if what are you looking for is a big one, and it is, it has a population of over 6 millions inhabitants.
About Santiago de Chile
Hospital El Pino
- Pontificia Universidad Catolica de Chile
- Universidad de Chile
- Universidad de Santiago de Chile
HOW TO GET THERE
You'll probably arrive by plane to Santiago de Chile and if you do so, you will arrive at the Aeropuerto Internacional Arturo Merino Benítez which was inaugurated around 50 years ago but it remains as one of the most modern and efficient airports in Latin America being a conection hub between all continents.
There's currently a project to expand the current Airport in around 200.000m^2 by 2020 with a whole new International section increasing the airport capacity to around 30millon passengers.
The best advice we can give you about is topic is as soon you get in Santiago de Chile, go straight to a any Metro Station and by a Bip! card (Ch$1.550, minimum recharge Ch$1000 [February, 2017]). This card is used for both subway and bus, and allows you free transfers between the two (you still have to swipe your card, but it's free of charge) in a 2 hour period.
Buses are mostly modern and run around the clock on the main lines. The only way to pay your fare is by bip!-card. You can buy this card and charge it in any metro station or in some stores. The card also allows you to travel by metro.
Parque Metropolitano- This vast park is home to Cerro San Cristóbal. From the top there is a beautiful view over the city and, on a clear day, the Andes. The summit can be reached by funicular ($900 one way, $1600 return), cable car, or a 40-60 minute hike. In the park there is also a botanical garden, zoo and two swimming pools. Pope John Paul II visited its summit in 1987.
Plaza De Armas- The capital's main plaza, also the site of the national cathedral and main post office. It's few blocks from the traditional Central Market and has its own Metro Station. During the last years, Plaza de Armas has been used as a meeting and recreation place for the community of Peruvian immigrants. This has lead to a lots of cheap international calling centers, traditional Peruvian restaurants and Peruvian spice and food stores, being an interesting place to walk during day hours.
Santiago Centro- The Centro (Downtown) area is a nice place for a stroll down some of its major Paseos (streets turned pedestrian walkways), but be aware of pickpockets.
La Chascona- One of three homes of the famous poet Pablo Neruda, La Chascona (meaning tangle-haired woman, after his third wife) is in the artistic Bellavista neighborhood. The house is filled with lots of quirky artifacts collected by Neruda throughout his life, as well as artwork by some of his famous friends. Tours are given in English, French ($3500) and Spanish ($2500). 
La Moneda Palace- Presidential Palace, guided one-hour tours are free, unfortunately with a reservation of at least 7 days in advance. (Spanish only)
Centro Cultural Palacio de La Moneda- An underground cultural center under the La Moneda Palace, with rotating art and cultural exhibitions all year. Local crafts and souvenirs are available at middle-high prices in the local gift shop. A café is also within the facilities. Note that most exhibitions are not free of charge, however, prices are very affordable.
Parque Forestal- A long park that runs parallel to the Mapocho River, also site of the National Museum of Fine Arts and Modern Art Museum.
Theatre & Dance- Santiago offers much in the performing arts, most takes place Friday & Saturday, check listings in El Mercurio. $500-5000 CLP, most offer discounts with student ID, even to foreigners, just ask.
Centro Cultural Matucana 100- Inaugurated in 2002, Matucana 100 is an excellent exhibition venue for a variety of arts. From Metro Quinta Normal, walk south on Matucana (towards Alameda), M100 is on the left hand side. 
Teatro Municipal- Historical performance venue, including international dance and opera, worth a visit even if just from its outside. 
Centro Cultural Gabriela Mistral (GAM)- An impressive-scale cultural center built on the former military Diego Portales building which was destroyed in a fire. The center has a art and film focused library with free WiFi, a theater, concert halls, a restaurant, a café, and public spaces for resting. Located on Universidad Católica metro station (Line 1). 
Jazz Clubs- Santiago is home to an impressive jazz scene, with several intimate clubs scattered throughout the city. The Club de Jazz de Santiago is arguably the best. Located in the northern part of the Nunoa neighborhood, this small club routinely brings in some of the best local, national, and international artists specializing in everything from latin jazz to blues to bossa nova. Check music listings in El Mercurio.
Festival de Jazz de Providencia- A very good jazz Festival takes place during summer (typically each February) in Providencia. The Festival de Jazz de Providencia takes place each year in Mapocho's riverside and showcasts the best local bands and some international guests. Tickets are cheap (from about 3 USD in the 2007 edition), so it's a good alternative for summer nights.
- Beachesare 90 minutes to the west in Viña del Mar, Valparaíso, Reñaca, etc.
- Ski resortsare 1 hour and a half to the east, like Valle Nevado, El Colorado, etc.
- Rancaguais 85 km to the south and has some thermal springs and hiking opportunities nearby.
- Cajon del Maipo, beautiful in spring, some 75 km south east of Santiago, day trip.Some nice places for lunch and tea; many of them only open on week-ends.
- Isla Negra, a village in the coast, south of Valparaíso. The main and most beloved house of Pablo Neruda is there. This is probably the most interesting of his three houses to visit and the best conserved as it is the only one that the military didn't sack during the coup of 1973. To get there, you can take the Pullman bus ($3700, 2h) from Santiago Alameda station (metro Universidad de Santiago). You can also take the Turbus bus to San Antonio ($1000 - $2000, 1h30) from Alameda as well, and then take a local bus in front of "laPolar" ($450, 30min) that goes along the beautiful coast. Tours in the house cost $3000 and last 30min. Then you can go to the beach.
- Sierras de Bellavista(150 Kms south of Santiago), wonderful little mountain village, especially after a rainy day. Alpine scenery.