Durango is the fourth largest state in the Mexican Republic. It is located in the beautiful Guadiana Valley, which is part of the UNESCO World Heritage Site and belongs to the Camino Real de Tierra Adentro.
The quality of its people, the variety of its gastronomy, its imposing natural landscapes, its affordable costs and its friendly climate allow CIFA UJED to invite you to the heart of Mexico.
Universidad Juarez del Estado de Durango, Faculty of Medicine and Nutrition, the only public university in this state
Hospital ISSSTE of Durango and IMSS Durango.
Antibacterial drug design. Finding inhibitors of enzymes from shikimate pathway in Staphylococcus aureus.
In this project we are interested in the development of a new drug against nosocomial bacteria. Our work focuses in two enzymes belong to the shikimate pathway, named shikimate kinase (SK) and shikimate dehydrogenase (SDH). This route is absent in humans; therefore their enzymes are excellent targets for drug design. To this end, we applied different methodologies such as molecular biology, biochemistry and computer assisted drug design. The project is centered in SK and SDH from Staphylococcus aureus, the most important pathogen in nosocomial infections worldwide. Aim of the Project The aim is to find inhibitors of both enzymes that could serve as a lead to design a new antibacterial drug, with high effectiveness that is useful to avoid resistance. Techniques that will be used. Some techniques that will be used are Polymerase chain reaction, Secoisolariciresinol diglucoside polyacrylamide gel electrophoresis (SDS PAGE), Protein purification, enzyme kinetics, homology modeling, molecular docking, molecular dynamics, and different spectroscopic techniques.
For more information, check the SCORE national EC and the project database
We will provide 2 meals per day in hospital.
Student flat/Host Family. In summer option for student apartment.
The public transport it’s very easy to use, the public bus cost nine pesos, we will teach you to use it, and you’ll not have troubles at all.
Durango it’s the city of movies in Mexico, You also will try different experience by going in the forest and there is a beach near of the city, Mazatlan.
Dresscode: White coat, white pants and white shoes, for laboratory only white coat is mandatory
- Bring your stethoscope and your scrubs
- You must cover 80% of the assistances in order to get your certificate.